Fizika Nizkikh Temperatur: Volume 46, Number 11 (November 2020), p. 1287-1291    ( to contents , go back )

On the measurements of magnetic nanoparticle concentration in a biological medium using a superconducting quantum magnetometer

S.I. Bondarenko1, O. G. Avrunin2, I. S. Bondarenko2, A. V. Krevsun1, V.P. Koverya1, and M. V. Rakhimova3

1B. Verkin Institute for Low Temperature Physics and Engineering of the National Academy of Sciences of Ukraine Kharkiv 61103, Ukraine
E-mail: bondarenko@ilt.kharkov.ua

2Kharkiv National University of Radio Electronics, Kharkiv 61000, Ukraine

3National University of Pharmacy, Kharkiv 61002, Ukraine
pos Анотація:

Received June 24, 2020, published online September 21, 2020

Abstract

Мagnetic nano-particles are used in medicine both as medical means, and for the transport of medicines in the pathological area of an organism. Simultaneous influence on these particles of ultrasonic radiation and a constant magnetic field allows summarising a magnetic field of an nano-particles ensemble to the value, sufficient for its registration by the remote magnetic detector. The parity connecting the measured magnetic flux of the nano-particles with parameters of the particles, ultrasound, and the measuring system using as the magnetic detector superconducting quantum magnetometer is received. Calculations have shown, that such a system can measure a concentration of the nano-particles in colloidal solution, modeling the biological medium, in the unattainable earlier dynamic range of values (from 1 vol % to 10–7 vol %).

Key words: superconducting quantum magnetometer, biological medium, magnetic nanoparticles, ultrasound radiation, colloidal solution.

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