Low Temperature Physics: 38, 311 (2012); https://doi.org/10.1063/1.3699954 (10 pages)
Fizika Nizkikh Temperatur: Volume 38, Number 4 (April 2012), p. 396-408    ( to contents , go back )

Application of SQUIDs for registration of biomagnetic signals

I.D. Voitovych, M.A. Primin, and V.N. Sosnytskyy

Glushkov Institute of Cybernetic of NAS of Ukraine, 40 Glushkova ave., Kyiv, Ukraine, 03187
E-mail: d220@meta.ua
pos Анотація:

Received Octouber 14, 2011

Abstract

Supersensitive magnetometric systems based on low-temperature SQUIDs have been designed to conduct research in cardiology (magnetocardiography) and to examine distribution of magnetic nanoparticles in biologic objects. Such SQUID magnetometric systems are distinguished by their noise immunity enabling research in nonscreened rooms. High repeatability of research outcomes has been confirmed. The use of magnetocardiographic systems have permitted a new screening information technology to be developed to diagnosie heart diseases at early stages. Magnetic imaging of heart’s action currents is an ideal way to test local electrical heterogeneity of myocardium. It is shown that magnetocardiography has a significant potential for both basic science of analysis of heart’s biosignals and clinical cardiologic practice. A SQUID magnetometric system measuring magnetic signals radiated by the organs of laboratory animals is described. An information technology registering and transforming automatically magnetometric data has been developed; the measurements of signals over rats’ livers while injecting intravenously the nanoparticles of iron oxides and lead solutions are presented.

PACS: 85.25.Dq Superconducting quantum interference devices (SQUIDs);
PACS: 87.15.–v Biomolecules: structure and physical properties.

Key words: SQUID magnetometer, biomagnetism, magnitocardiography, express-diagnostic, nanoparticles.

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